| Customization: | Available |
|---|---|
| CAS No.: | 22260-51-1 |
| Formula: | C33h44brn5o8s |
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DESCRIPTION
Bromocriptine mesylate is an ergot derivative with potent dopamine receptor agonist activity. Bromocriptine mesylate is chemically designated as 2-bromoergocryptine monomethanesulfonate (salt).* Bromocriptine mesylate is a white or slightly colored, fine crystalline powder odorless or having a weak characteristic odor.
Bromocriptine mesylate is a dopamine receptor agonist, which activates postsynaptic dopamine receptors. The dopaminergic neurons in the tuberoinfundibular process modulate the secretion of prolactin from the anterior pituitary by secreting a prolactin inhibitory factor (thought to be dopamine); in the corpus striatum the dopaminergic neurons are involved in the control of motor function. Clinically, bromocriptine mesylate significantly reduces plasma levels of prolactin in patients with physiologically elevated prolactin as well as in patients with hyperprolactinemia. The inhibition of physiological lactation as well as galactorrhea in pathological hyperprolactine-mic states is obtained at dose levels that do not affect secretion of other tropic hormones from the anterior pituitary. Experiments have demonstrated that bromocriptine induces long lasting stereotyped behavior in rodents and turning behavior in rats having unilateral lesions in the substantia nigra. These actions, characteristic of those produced by dopamine, are inhibited by dopamine antagonists and suggest a direct action of bromocriptine on striataldopamine receptors. Bromocriptine mesylate is a nonhormonal, nonestrogenic agent that inhibits the secretion of prolactin in humans, with little or no effect on other pituitary hormones, except in patients with acromegaly, where it lowers elevated blood levels of growth hormone in the majority of patients.
Structural Formula
SPECIFICATIONS
Appearance: White to off white crystal powder, afraid of light
Loss on Drying: 4.0%max
Residue on ignition: 0.1%max
Heavy metals: 20ppm max
Assay: 98.0-102.0%
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2. Large capacity of stable materials supply;
3. Safety and fast shipment by express/air/sea;
4. Sample order acceptable;
5. Professional and great packing as customized;
6. Convenient payment terms by T/T, Credit Card and online order;
7. Reply inquiries in time
Q: Who are you?
A: We are a professional and with more than 20 years experienced supplier and exporter for Industrial & fine chemicals, APIs, Reagent & Lab Supplies, and Food & Food Additives in China.
Q: How can you guarantee quality?
A: We could provide pre-production sample before mass production. And we also accept the final inspection(third-party) before shipment.
Q: Do you supply free samples?
A: Generally, we could provide free sample for quality evaluation, but the international shipping cost should be undertook by customers.
Q: Which payment terms do you accept?
A: We could accept the payment through T/T, L/C and Online payment.
Q: Can I pay with a credit card
A: Yes, you could feel free to make your payment through credit card. Please contact us for more details
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