| Customization: | Available |
|---|---|
| CAS No.: | 18439-24-2 |
| Formula: | C21h33li3n7o16p3s |
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Coenzyme A, Trilithium Salt, CAS 18439-24-2, serves as a cofactor in enzymatic acetyl transfer reactions.
Coenzyme A (CoA) (Trilithium Salt) is supplied as a crystalline solid. Organic solvent-free aqueous solutions of CoA (Trilithium Salt) can be prepared by directly dissolving the crystalline solid in aqueous buffers. The solubility of CoA (Trilithium Salt) in PBS, pH 7.2, is approximately 10 mg/ml. We do not recommend storing the aqueous solution for more than one day.
CoA is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism.1 About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid (Item No. 17288) in a five-step process that requires ATP.2 The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds.
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